TABLE 1:

Breed, C4, serum cobalamin concentration and clinical features of the control and clinical cases

BreedAge (years)Cobalamin (pg/ml)
Normal >200
C4 (nmol/l)Canine chronic enteropathy activity indexDiagnosis
Clinically healthy dogs
 Border terrier2.7N/A15.1N/AN/A
 Hungarian vizsla1.7N/A22.7N/AN/A
 Labrador retriever5.0N/A29.9N/AN/A
 Lurcher3.0N/A35.9N/AN/A
 Golden retriever2.0N/A40.0N/AN/A
 Cross breed7.0N/A41.1N/AN/A
 Cocker spaniel2.5N/A8.9N/AN/A
 Labrador cross8.2N/A58.8N/AN/A
 Yorkshire terrier1.3N/A74.8N/AN/A
 Labrador retriever6.0N/A77.2N/AN/A
 German shepherd dog9.0N/A84.6N/AN/A
 Rottweiler8.0N/A100.4N/AN/A
 Schnauzer8.0N/A105.0N/AN/A
 Japanese spitz4.5N/A105.3N/AN/A
 Labrador retriever3.0N/A108.2N/AN/A
 Labrador retriever10.0N/A143.0N/AN/A
 Labrador retriever12.0N/A146.5N/AN/A
 Shiba inu9.0N/A164.0N/AN/A
 Mastiff1.1N/A176.5N/AN/A
 Boxer9.5N/A180.2N/AN/A
Group median5.5N/A80.9
Clinical cases
 Greyhound8.052321.36IBD
 Tibetan terrier10.033825.113IBD
 Miniature poodle4.055625.88IBD
 Wheaten terrier7.019926.215IBD
 Greyhound10.012134.27IBD
 Cocker spaniel8.083437.15ARE
 German shepherd dog4.2521740.16ARE
 Airedale terrier5.033843.95DRE
 German shepherd dog2.944359.95EPI
 Staffordshire bull ter.9.5162119.812IBD
 Miniature schnauzer9.0272120.011IBD
 Rottweiler1.5558129.35IBD
 Rottweiler8.8190178.94DRE
 Shiba inu12.0353194.37Coronavirus
 Jack Russell ter. cross5.0310362.710IBD
 Border collie6.0100438.09IBD
 Border terrier11.0550518.66IBD
Group median8.033859.97
  • ARE, antibiotic-responsive enteropathy; DRE, diet-responsive enteropathy; EPI, exocrine pancreatic insufficiency; IBD, inflammatory bowel disease; N/A, not applicable